BREAKING DOWN BIOLOGY

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BREAKDOWN BIO and NASA Execute Licensing Agreement

Breakthrough Microbial Technology, Unlocking New Possibilities for Space and Earth.

MERCED, CA, March 10, 2025 — Breakdown Bio, a trailblazing biotechnology startup, proudly announces a transformative license agreement with NASA. This collaboration brings a revolutionary microbial technology from NASA Ames Research Center into Breakdown Bio’s hands, offering unparalleled benefits for sustainable resource production in space and beyond.

Game-Changing Benefits of the Technology

This cutting-edge technology stands out for its robust and cost-effective approach to bio-manufacturing. At its core are unique microorganisms that serve as self-replicating bio-factories, capable of producing both native and engineered bio-products tailored to mission-critical needs. These bio-factories harness readily available carbon sources—such as carbon dioxide and methane—to create a sustainable production system that thrives in resource-scarce environments like space.

A standout feature is the ability to recapture lost methane in space and repurpose it for microbial manufacturing. This innovative approach could redefine in-space bio-manufacturing, turning waste into valuable resources. The technology also integrates seamlessly with existing flight-approved systems, such as the Sabatier process, by coupling its waste streams to new bio-manufacturing systems. Beyond Sabatier, methane could be sourced from a variety of physico-chemical and non-physico-chemical technologies, further enhancing flexibility.

The microorganisms generate mission-relevant bio-products with unique capabilities, including:

  • Materials for habitat construction to support long-term space living.

  • Nutritional resources for astronauts to sustain health during missions.

  • Biomedical applications to address health challenges in space.

Designed to be scalable, programmable, and regenerable, this system adapts to evolving demands, ensuring longevity and versatility for both short- and long-term applications.

Applications Across Space and Earth

The potential of this technology spans multiple sectors:

  • Space Industry:

  1. Habitat Construction: Enabling durable, sustainable living spaces for astronauts.

  2. Astronaut Nutrition: Producing essential nutrients on-site to reduce reliance on Earth resupply.

  3. Biomedical Applications: Supporting astronaut health with tailored bio-products.

  • Terrestrial Methane-Based Microbial Bio-Manufacturing:

    Leveraging methane as a carbon source, this technology offers sustainable solutions for industries aiming to reduce waste and enhance resource efficiency on Earth.

  • Biotechnology Industry:

    Opening new pathways for bio-product innovation, with applications ranging from healthcare to industrial manufacturing.

"This technology’s ability to turn abundant resources like methane and carbon dioxide into mission-critical products is a leap forward," said Jesse, CTO of Breakdown Bio. "By coupling it with proven systems and recapturing lost methane, we’re building a foundation for sustainable exploration in space and groundbreaking advancements on Earth."

A Vision for the Future

Breakdown Bio is committed to pushing this technology to its full potential in collaboration with NASA. The company envisions a future where these robust, cost-effective bio-factories empower humanity to thrive in space while driving innovation in terrestrial markets.

About Breakdown Bio: Breakdown Bio is a biotechnology startup focused on sustainable resource solutions for extreme environments. Through cutting-edge bioengineering and strategic partnerships, the company is shaping the future of resource production.

About NASA's Technology Transfer Program: NASA’s Technology Transfer Program shares space-developed innovations with the public, enabling companies like Breakdown Bio to create impactful solutions for humanity.

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For media inquiries, contact team@breakdownbio.com.

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